Clinical Trials Detalhe

The primary objective of the RIC-STEMI trial is to assess whether remote ischaemic conditioning (RIC) as an adjunctive therapy during primary percutaneous coronary intervention (PCI) in patients presenting with ST-elevation myocardial infarction (STEMI) can improve clinical outcomes as assessed by death from cardiac-cause or hospitalization for heart failure (HF) for a minimum follow-up period of 12 months.

ST Elevation Myocardial Infarction

Inclusion Criteria: * STEMI defined as chest pain (or epigastric pain) for more than 30 minutes and either: (i) new ST elevation at the J point in two contiguous leads with the cut-off points of ≥0.2 mV in men or ≥0.15 mV in women in leads V2-V3 or ≥0.1 mV in all other leads, (ii) or new or presumed new left bundle branch block (LBBB) * Symptom onset not more than 12 h before presentation * Willingness and capability to provide informed consent Exclusion Criteria: * Cardiogenic shock as defined by systemic hypotension (systolic arterial pressure - SAP - below 90 mmHg) and evidence of tissue hypoperfusion * Post-cardiac arrest status * Need for mechanical ventilation * Known peripheral artery disease or evidence of lower limb ischemia * Recent myocardial infarction (within 30 days)